Pharmacology, PK, and PD profiles

All profiles in the Pharmacology, PK, and PD domain, version 0.1.0-alpha.5. The Review column shows each profile’s review status. In this release every profile is candidate or draft, and none has been scientifically reviewed yet. A profile describes whether two ports fit together; it does not establish scientific validity or clinical safety.

Profile	Name	Stage	Review	Required items
Area Under Curve	area-under-curve	WAVE_2	candidate	6
Association Rate	association-rate	WAVE_2	candidate	7
Binding Affinity	binding-affinity	WAVE_2	candidate	7
Clearance	clearance	WAVE_2	candidate	4
Compound Dose	compound-dose	WAVE_2	candidate	7
Concentration Response Curve	concentration-response-curve	WAVE_2	candidate	9
Dissociation Constant	dissociation-constant	WAVE_2	candidate	4
Dissociation Rate	dissociation-rate	WAVE_2	candidate	7
Dose Response Curve	dose-response-curve	WAVE_2	candidate	9
Dose Schedule	dose-schedule	WAVE_2	candidate	7
EC50	ec50	WAVE_2	candidate	4
Efficacy	efficacy	WAVE_2	candidate	4
Emax	emax	WAVE_2	candidate	4
Exposure Concentration	exposure-concentration	WAVE_2	candidate	7
Hill Coefficient	hill-coefficient	WAVE_2	candidate	4
IC50	ic50	WAVE_2	candidate	4
Inhibition Constant	inhibition-constant	WAVE_2	candidate	4
Pharmacodynamic Parameters	pharmacodynamic-parameters	WAVE_2	candidate	4
Pharmacokinetic Parameters	pharmacokinetic-parameters	WAVE_2	candidate	4
Plasma Concentration	plasma-concentration	WAVE_2	candidate	7
Potency	potency	WAVE_2	candidate	4
Receptor Occupancy	receptor-occupancy	WAVE_2	candidate	4
Target Engagement	target-engagement	WAVE_2	candidate	4
Tissue Concentration	tissue-concentration	WAVE_2	candidate	7
Volume of Distribution	volume-of-distribution	WAVE_2	candidate	9

Each profile links to its JSON definition. See the catalogue for search, filters and what the Stage and Review columns mean.