# Transcriptome and RNA profiles All profiles in the Transcriptome and RNA domain, version 0.1.0-alpha.5. The Review column shows each profile's review status. In this release every profile is candidate or draft, and none has been scientifically reviewed yet. A profile describes whether two ports fit together; it does not establish scientific validity or clinical safety. | Profile | Name | Stage | Review | Required items | |---|---|---:|---:|---:| | [Alternative Splicing Event](/standards/model-compatibility/profiles/transcriptome/alternative-splicing-event/v0.1.json) | `alternative-splicing-event` | WAVE_2 | candidate | 4 | | [Differential Expression](/standards/model-compatibility/profiles/transcriptome/differential-expression/v0.1.json) | `differential-expression` | WAVE_2 | candidate | 4 | | [Expression Signature](/standards/model-compatibility/profiles/transcriptome/expression-signature/v0.1.json) | `expression-signature` | WAVE_2 | candidate | 4 | | [Expression Trajectory](/standards/model-compatibility/profiles/transcriptome/expression-trajectory/v0.1.json) | `expression-trajectory` | WAVE_2 | candidate | 6 | | [Fold Change Vector](/standards/model-compatibility/profiles/transcriptome/fold-change-vector/v0.1.json) | `fold-change-vector` | WAVE_2 | candidate | 6 | | [Gene Expression Counts](/standards/model-compatibility/profiles/transcriptome/gene-expression-counts/v0.1.json) | `gene-expression-counts` | WAVE_2 | candidate | 6 | | [Gene Set Activity](/standards/model-compatibility/profiles/transcriptome/gene-set-activity/v0.1.json) | `gene-set-activity` | WAVE_2 | candidate | 6 | | [lncRNA Expression](/standards/model-compatibility/profiles/transcriptome/lncrna-expression/v0.1.json) | `lncrna-expression` | WAVE_2 | candidate | 4 | | [microRNA Expression](/standards/model-compatibility/profiles/transcriptome/microrna-expression/v0.1.json) | `microrna-expression` | WAVE_2 | candidate | 4 | | [Nascent Transcription](/standards/model-compatibility/profiles/transcriptome/nascent-transcription/v0.1.json) | `nascent-transcription` | WAVE_2 | candidate | 4 | | [Normalized Gene Expression](/standards/model-compatibility/profiles/transcriptome/normalized-gene-expression/v0.1.json) | `normalized-gene-expression` | WAVE_2 | candidate | 6 | | [Pathway Activity](/standards/model-compatibility/profiles/transcriptome/pathway-activity/v0.1.json) | `pathway-activity` | WAVE_2 | candidate | 4 | | [Pseudobulk Expression](/standards/model-compatibility/profiles/transcriptome/pseudobulk-expression/v0.1.json) | `pseudobulk-expression` | WAVE_2 | candidate | 4 | | [RNA Editing Event](/standards/model-compatibility/profiles/transcriptome/rna-editing-event/v0.1.json) | `rna-editing-event` | WAVE_2 | candidate | 4 | | [RNA Sequence](/standards/model-compatibility/profiles/transcriptome/rna-sequence/v0.1.json) | `rna-sequence` | WAVE_2 | candidate | 6 | | [RNA Structure](/standards/model-compatibility/profiles/transcriptome/rna-structure/v0.1.json) | `rna-structure` | WAVE_2 | candidate | 4 | | [RNA Velocity](/standards/model-compatibility/profiles/transcriptome/rna-velocity/v0.1.json) | `rna-velocity` | WAVE_2 | candidate | 4 | | [Single-cell Expression Matrix](/standards/model-compatibility/profiles/transcriptome/single-cell-expression-matrix/v0.1.json) | `single-cell-expression-matrix` | WAVE_2 | candidate | 6 | | [Small RNA Abundance](/standards/model-compatibility/profiles/transcriptome/small-rna-abundance/v0.1.json) | `small-rna-abundance` | WAVE_2 | candidate | 7 | | [Spatial Transcriptomics Matrix](/standards/model-compatibility/profiles/transcriptome/spatial-transcriptomics-matrix/v0.1.json) | `spatial-transcriptomics-matrix` | WAVE_2 | candidate | 6 | | [Splice Junction Counts](/standards/model-compatibility/profiles/transcriptome/splice-junction-counts/v0.1.json) | `splice-junction-counts` | WAVE_2 | candidate | 4 | | [Transcript Expression](/standards/model-compatibility/profiles/transcriptome/transcript-expression/v0.1.json) | `transcript-expression` | WAVE_2 | candidate | 4 | | [Transcript Isoform Usage](/standards/model-compatibility/profiles/transcriptome/transcript-isoform-usage/v0.1.json) | `transcript-isoform-usage` | WAVE_2 | candidate | 4 | | [Transcription Factor Activity](/standards/model-compatibility/profiles/transcriptome/transcription-factor-activity/v0.1.json) | `transcription-factor-activity` | WAVE_2 | candidate | 4 | | [Transcriptional State](/standards/model-compatibility/profiles/transcriptome/transcriptional-state/v0.1.json) | `transcriptional-state` | WAVE_2 | candidate | 4 | Each profile links to its JSON definition. See the [catalogue](/standards/model-compatibility/catalogue) for search, filters and what the Stage and Review columns mean.