# Pharmacology, PK, and PD profiles All profiles in the Pharmacology, PK, and PD domain, version 0.1.0-alpha.5. The Review column shows each profile's review status. In this release every profile is candidate or draft, and none has been scientifically reviewed yet. A profile describes whether two ports fit together; it does not establish scientific validity or clinical safety. | Profile | Name | Stage | Review | Required items | |---|---|---:|---:|---:| | [Area Under Curve](/standards/model-compatibility/profiles/pharmacology/area-under-curve/v0.1.json) | `area-under-curve` | WAVE_2 | candidate | 6 | | [Association Rate](/standards/model-compatibility/profiles/pharmacology/association-rate/v0.1.json) | `association-rate` | WAVE_2 | candidate | 7 | | [Binding Affinity](/standards/model-compatibility/profiles/pharmacology/binding-affinity/v0.1.json) | `binding-affinity` | WAVE_2 | candidate | 7 | | [Clearance](/standards/model-compatibility/profiles/pharmacology/clearance/v0.1.json) | `clearance` | WAVE_2 | candidate | 4 | | [Compound Dose](/standards/model-compatibility/profiles/pharmacology/compound-dose/v0.1.json) | `compound-dose` | WAVE_2 | candidate | 7 | | [Concentration Response Curve](/standards/model-compatibility/profiles/pharmacology/concentration-response-curve/v0.1.json) | `concentration-response-curve` | WAVE_2 | candidate | 9 | | [Dissociation Constant](/standards/model-compatibility/profiles/pharmacology/dissociation-constant/v0.1.json) | `dissociation-constant` | WAVE_2 | candidate | 4 | | [Dissociation Rate](/standards/model-compatibility/profiles/pharmacology/dissociation-rate/v0.1.json) | `dissociation-rate` | WAVE_2 | candidate | 7 | | [Dose Response Curve](/standards/model-compatibility/profiles/pharmacology/dose-response-curve/v0.1.json) | `dose-response-curve` | WAVE_2 | candidate | 9 | | [Dose Schedule](/standards/model-compatibility/profiles/pharmacology/dose-schedule/v0.1.json) | `dose-schedule` | WAVE_2 | candidate | 7 | | [EC50](/standards/model-compatibility/profiles/pharmacology/ec50/v0.1.json) | `ec50` | WAVE_2 | candidate | 4 | | [Efficacy](/standards/model-compatibility/profiles/pharmacology/efficacy/v0.1.json) | `efficacy` | WAVE_2 | candidate | 4 | | [Emax](/standards/model-compatibility/profiles/pharmacology/emax/v0.1.json) | `emax` | WAVE_2 | candidate | 4 | | [Exposure Concentration](/standards/model-compatibility/profiles/pharmacology/exposure-concentration/v0.1.json) | `exposure-concentration` | WAVE_2 | candidate | 7 | | [Hill Coefficient](/standards/model-compatibility/profiles/pharmacology/hill-coefficient/v0.1.json) | `hill-coefficient` | WAVE_2 | candidate | 4 | | [IC50](/standards/model-compatibility/profiles/pharmacology/ic50/v0.1.json) | `ic50` | WAVE_2 | candidate | 4 | | [Inhibition Constant](/standards/model-compatibility/profiles/pharmacology/inhibition-constant/v0.1.json) | `inhibition-constant` | WAVE_2 | candidate | 4 | | [Pharmacodynamic Parameters](/standards/model-compatibility/profiles/pharmacology/pharmacodynamic-parameters/v0.1.json) | `pharmacodynamic-parameters` | WAVE_2 | candidate | 4 | | [Pharmacokinetic Parameters](/standards/model-compatibility/profiles/pharmacology/pharmacokinetic-parameters/v0.1.json) | `pharmacokinetic-parameters` | WAVE_2 | candidate | 4 | | [Plasma Concentration](/standards/model-compatibility/profiles/pharmacology/plasma-concentration/v0.1.json) | `plasma-concentration` | WAVE_2 | candidate | 7 | | [Potency](/standards/model-compatibility/profiles/pharmacology/potency/v0.1.json) | `potency` | WAVE_2 | candidate | 4 | | [Receptor Occupancy](/standards/model-compatibility/profiles/pharmacology/receptor-occupancy/v0.1.json) | `receptor-occupancy` | WAVE_2 | candidate | 4 | | [Target Engagement](/standards/model-compatibility/profiles/pharmacology/target-engagement/v0.1.json) | `target-engagement` | WAVE_2 | candidate | 4 | | [Tissue Concentration](/standards/model-compatibility/profiles/pharmacology/tissue-concentration/v0.1.json) | `tissue-concentration` | WAVE_2 | candidate | 7 | | [Volume of Distribution](/standards/model-compatibility/profiles/pharmacology/volume-of-distribution/v0.1.json) | `volume-of-distribution` | WAVE_2 | candidate | 9 | Each profile links to its JSON definition. See the [catalogue](/standards/model-compatibility/catalogue) for search, filters and what the Stage and Review columns mean.