# Epigenome and regulation profiles All profiles in the Epigenome and regulation domain, version 0.1.0-alpha.5. The Review column shows each profile's review status. In this release every profile is candidate or draft, and none has been scientifically reviewed yet. A profile describes whether two ports fit together; it does not establish scientific validity or clinical safety. | Profile | Name | Stage | Review | Required items | |---|---|---:|---:|---:| | [Allele Specific Methylation](/standards/model-compatibility/profiles/epigenome/allele-specific-methylation/v0.1.json) | `allele-specific-methylation` | WAVE_2 | candidate | 4 | | [ATAC Peak Counts](/standards/model-compatibility/profiles/epigenome/atac-peak-counts/v0.1.json) | `atac-peak-counts` | WAVE_2 | candidate | 4 | | [ChIP-seq Peaks](/standards/model-compatibility/profiles/epigenome/chip-seq-peaks/v0.1.json) | `chip-seq-peaks` | WAVE_2 | candidate | 4 | | [Chromatin Accessibility](/standards/model-compatibility/profiles/epigenome/chromatin-accessibility/v0.1.json) | `chromatin-accessibility` | WAVE_2 | candidate | 4 | | [Chromatin Contact Matrix](/standards/model-compatibility/profiles/epigenome/chromatin-contact-matrix/v0.1.json) | `chromatin-contact-matrix` | WAVE_2 | candidate | 6 | | [Chromatin State](/standards/model-compatibility/profiles/epigenome/chromatin-state/v0.1.json) | `chromatin-state` | WAVE_2 | candidate | 4 | | [CpG Methylation Profile](/standards/model-compatibility/profiles/epigenome/cpg-methylation-profile/v0.1.json) | `cpg-methylation-profile` | WAVE_2 | candidate | 4 | | [DNA Methylation Fraction](/standards/model-compatibility/profiles/epigenome/dna-methylation-fraction/v0.1.json) | `dna-methylation-fraction` | WAVE_2 | candidate | 7 | | [Enhancer Activity](/standards/model-compatibility/profiles/epigenome/enhancer-activity/v0.1.json) | `enhancer-activity` | WAVE_2 | candidate | 4 | | [Epigenetic Clock](/standards/model-compatibility/profiles/epigenome/epigenetic-clock/v0.1.json) | `epigenetic-clock` | WAVE_2 | candidate | 6 | | [Epigenetic Trajectory](/standards/model-compatibility/profiles/epigenome/epigenetic-trajectory/v0.1.json) | `epigenetic-trajectory` | WAVE_2 | candidate | 8 | | [Footprint Score](/standards/model-compatibility/profiles/epigenome/footprint-score/v0.1.json) | `footprint-score` | WAVE_2 | candidate | 7 | | [Hi-C Contact Map](/standards/model-compatibility/profiles/epigenome/hic-contact-map/v0.1.json) | `hic-contact-map` | WAVE_2 | candidate | 6 | | [Histone Modification Signal](/standards/model-compatibility/profiles/epigenome/histone-modification-signal/v0.1.json) | `histone-modification-signal` | WAVE_2 | candidate | 4 | | [Methylation Age](/standards/model-compatibility/profiles/epigenome/methylation-age/v0.1.json) | `methylation-age` | WAVE_2 | candidate | 4 | | [Methylation Beta Value](/standards/model-compatibility/profiles/epigenome/methylation-beta-value/v0.1.json) | `methylation-beta-value` | WAVE_2 | candidate | 7 | | [Methylation M Value](/standards/model-compatibility/profiles/epigenome/methylation-m-value/v0.1.json) | `methylation-m-value` | WAVE_2 | candidate | 7 | | [Motif Accessibility](/standards/model-compatibility/profiles/epigenome/motif-accessibility/v0.1.json) | `motif-accessibility` | WAVE_2 | candidate | 4 | | [Nucleosome Positioning](/standards/model-compatibility/profiles/epigenome/nucleosome-positioning/v0.1.json) | `nucleosome-positioning` | WAVE_2 | candidate | 4 | | [Promoter Activity](/standards/model-compatibility/profiles/epigenome/promoter-activity/v0.1.json) | `promoter-activity` | WAVE_2 | candidate | 4 | | [Regulatory Element Annotation](/standards/model-compatibility/profiles/epigenome/regulatory-element-annotation/v0.1.json) | `regulatory-element-annotation` | WAVE_2 | candidate | 4 | | [Single-cell Epigenome](/standards/model-compatibility/profiles/epigenome/single-cell-epigenome/v0.1.json) | `single-cell-epigenome` | WAVE_2 | candidate | 4 | | [Spatial Epigenome](/standards/model-compatibility/profiles/epigenome/spatial-epigenome/v0.1.json) | `spatial-epigenome` | WAVE_2 | candidate | 4 | | [Topological Domain](/standards/model-compatibility/profiles/epigenome/topological-domain/v0.1.json) | `topological-domain` | WAVE_2 | candidate | 4 | | [Transcription Factor Binding](/standards/model-compatibility/profiles/epigenome/transcription-factor-binding/v0.1.json) | `transcription-factor-binding` | WAVE_2 | candidate | 4 | Each profile links to its JSON definition. See the [catalogue](/standards/model-compatibility/catalogue) for search, filters and what the Stage and Review columns mean.